LeBron James’ first game as a member of the Philadelphia 76ers will come at the world’s most famous arena.James’ 76ers will take on the defending NBA champion New York Knicks on Oct. 20 at 7 p.m. ET at Madison Square Garden on the NBA’s opening night of the 2026-27 season. Knicks-76ers is the first of three games on the NBA’s opening night.The NBA season will begin when the Boston Celtics take on the Detroit Pistons at 3 p.m. ET and conclude when the Oklahoma City Thunder take on the San Antonio Spurs at 9:30 p.m. ET.CLICK HERE FOR MORE SPORTS COVERAGE ON FOXNEWS.COMThe Knicks-76ers matchup is a rematch of the 2026 Eastern Conference semifinals, a series in which the Knicks swept the 76ers in four games.The Knicks are returning most of the same core that dominated the NBA playoffs and won the title, with the only notable loss being backup center and defensive stalwart Mitchell Robinson. Robinson signed a three-year, $47.38 million contract with the Celtics.ZERO BS. JUST DAKICH. TAKE THE DON’T @ ME PODCAST ON THE ROAD. DOWNLOAD NOW!The 76ers, however, will look much different on opening night. Not only did they sign James, but they also pulled off a stunning trade for Celtics star Jaylen Brown.They acquired the 2024 Finals MVP for Paul George, a 2028 first-round pick, a 2031 first-round pick, a 2028 second-round pick (best of the Golden State Warriors/Oklahoma City Thunder/Milwaukee Bucks) and a 2030 second-round pick (best of the Washington Wizards/Portland Trail Blazers/Phoenix Suns).With the additions of Brown and James, the 76ers’ starting lineup will likely be composed of VJ Edgecomb, Tyrese Maxey, Brown, James and Joel Embiid, forming one of the strongest lineups in the Eastern Conference.The 76ers’ revamped starting lineup’s first task will be taking down the reigning NBA champions on their home floor.Follow Fox News Digital’s sports coverage on X, and subscribe to the Fox News Sports Huddle newsletter.