Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular βantennaeβ in key brain cells, restoring vital dopamine communication and neuroprotective signals in a mouse model of genetic Parkinsonβs. After three months on the LRRK2-blocking drug MLi-2, damaged circuits revived and early signs of neuronal recovery emerged, hinting that timely treatment could not only halt but reverse disease progressionβand perhaps benefit other Parkinsonβs forms.
ScienceDaily
Rainforest deaths are surging and scientists just found the shocking cause
Tropical trees are dying faster than ever, and it’s not just heat or drought to blame. Scientists have uncovered a surprising culprit: ordinary thunderstorms. These quick, fierce storms, powered by climate change, are toppling trees with intense winds and lightning, sometimes causing more damage than drought itself. The discovery is reshaping how we understand rainforest health and carbon storage, as storms may be responsible for up to 60% of tree deaths in some regions. Researchers now warn that failing to account for this hidden force could undermine forest conservation and climate models alike.
Even low levels of air pollution may quietly scar your heart, MRI study finds
Breathing polluted airβeven at levels considered βsafeββmay quietly damage your heart. A new study using advanced MRI scans found that people exposed to more air pollution showed early signs of scarring in their heart muscle, which can lead to heart failure over time. This damage showed up in both healthy individuals and people with heart conditions, and was especially noticeable in women, smokers, and those with high blood pressure.
AI spots deadly heart risk most doctors can’t see
An advanced Johns Hopkins AI model called MAARS combs through underused heart MRI scans and complete medical records to spot hidden scar patterns that signal sudden cardiac death, dramatically outperforming current dice-roll clinical guidelines and promising to save lives while sparing patients unnecessary defibrillators.
A star exploded twice β First-ever image reveals its cosmic fingerprint
Astronomers studying the remnant SNR 0509-67.5 have finally caught a white dwarf in the act of a rare βdouble-detonationβ supernova, where an initial helium blast on the starβs surface triggers a second, core-shattering explosion.
The fatal mutation that lets cancer outsmart the human immune system
Scientists at UC Davis discovered a small genetic difference that could explain why humans are more prone to certain cancers than our primate cousins. The change affects a protein used by immune cells to kill tumorsβexcept in humans, itβs vulnerable to being shut down by an enzyme that tumors release. This flaw may be one reason treatments like CAR-T donβt work as well on solid tumors. The surprising twist? That mutation might have helped our brains grow larger over time. Now, researchers are exploring ways to block the enzyme and give our immune system its power back.
A midlife MRI that spots rapid aging and signals disease long before symptoms
A new brain scan tool shows how quickly your body and mind are aging. It can spot early signs of diseases like dementia, long before symptoms begin. The scan looks at hidden clues in your brain to predict future health.
The pandemic pet boom was real. The happiness boost wasnβt
Locked-down Hungarians who gained or lost pets saw almost no lasting shift in mood or loneliness, and new dog owners actually felt less calm and satisfied over timeβhinting that the storied βpet effectβ may be more myth than mental-health remedy even in extreme isolation.
Tiny gut βspongeβ bacteria found to flush out toxic PFAS βforever chemicalsβ
Cambridge scientists have spotted gut bacteria that greedily soak up PFAS βforever chemicals,β then ferry them safely out of the body in animal tests, removing up to three-quarters of the toxins within minutes. Their findings hint at probiotic pills that could shield people from PFAS-linked cancers, fertility issues, and heart disease while lawmakers scramble to rein in 4,700 widespread compounds.
Citizen scientists spot rare exploding star in real-time
Citizen scientists using the Kilonova Seekers platform spotted a stellar flash 2,500 times brighter than before, allowing astronomers to identify the exploding cataclysmic variable GOTO0650 within hours. Swift community follow-up captured X-ray, UV, and amateur telescope data, revealing the starβs rare βperiod-bouncerβ stage.