There may be a promising new treatment on the horizon for advanced breast cancer patients, according to developing research.Researchers are studying the cancer-killing drug trastuzmab rezetecan for those with ERBB2-low metastatic breast cancer, whose tumors have low levels of HER2, a protein that can help cancer cells grow.A phase 3 clinical trial called HORIZON-Breast06 sought to determine whether the drug works better than standard chemotherapy for patients with this cancer type.SHIFT IN CANCER SCREENING GUIDANCE HAS EXPERTS CLASHING OVER NEW GUIDANCEThe researchers analyzed 551 female patients across 73 hospitals in China who were randomly assigned to receive either the drug intravenously every three weeks, or the physician’s choice of chemotherapy. The study period lasted from June 2023 to August 2025.The drug significantly delayed cancer progression compared with chemotherapy, giving patients more than a year before their cancer began growing again.The median time without tumor growth was 16.4 months compared to 6.8 months with chemo.FDA APPROVES ONCE-DAILY PILL FOR DEADLY CANCER AFTER PATIENTS’ SURVIVAL RATES NEARLY DOUBLEPatients who received trastuzumab rezetecan were 73% less likely to have their cancer worsen or die during the study than patients who received chemotherapy.The drug appeared to delay cancer progression in patients with both hormone receptor-positive and hormone receptor-negative breast cancer.The results were published in JAMA.Tumors shrank in 75.5% of patients who received the drug, compared with 41.2% of those who received chemotherapy.At the 12-month mark, 90.6% of trastuzmab rezetecan patients were alive, compared to 81.4% of chemo patients.CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTERThe authors concluded that trastuzumab rezetecan provided “significant progression-free survival benefit over physician’s choice of chemotherapy in patients with ERBB2-low advanced breast cancer.”Loren Rourke, a Texas-based breast surgical oncologist and author in Texas, called the results “incredibly encouraging.””When you’re talking about women living with advanced breast cancer, those months matter,” Rourke, who was not involved in the study, told Fox News Digital. “They represent more time when the cancer is being held in check and potentially more opportunities to enjoy life without the disease getting worse.”What makes these findings especially exciting, according to the oncologist, is that the treatment showed benefits across different types of breast cancer.CLICK HERE FOR MORE HEALTH STORIES”It’s another important step forward, and it gives us genuine reason to be hopeful,” she said. “A treatment that can keep cancer from progressing for a longer period has the potential to make an enormous difference in a patient’s life.”While the drug may cause fewer serious lung problems than similar treatments, it was linked to other side effects, including anemia and other blood-related problems.Serious side effects occurred in more than 84% of patients who received the new drug, compared with nearly 68% of those who received chemotherapy.Rourke emphasized the importance of considering the side effects, “because more time without cancer progression doesn’t automatically mean better quality of life.””We need to better understand the side effects, particularly the significant decreases in blood counts that can lead to fatigue, anemia and increased risk of infection,” she said.The researchers acknowledged that toxicity occurred more frequently and often required dose modification, although they said these effects were “generally manageable.”TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZThe experts agreed that more research is needed.”As exciting as these findings are, there are still important questions we need to answer,” Rourke told Fox News Digital. “We know this treatment delayed cancer progression, but we don’t yet know whether it will help patients live longer. That’s an important distinction.””It’s important to celebrate meaningful progress while making sure we’re asking the right questions about what comes next.”
Cruz says there’s ‘real risk that Americans will die’ if El-Sayed gains access to US intelligence
Sen. Ted Cruz, R-Texas, suggested that Americans could die if Michigan Democratic Senate candidate Abdul El-Sayed is elected, suggesting that the Democrat could use U.S. intelligence to tip off terrorists.”If Abdul El-Sayed becomes the senator from Michigan, there is absolutely nothing to stop Chuck Schumer from placing Abdul El-Sayed on the Senate Intelligence Committee. The Senate Intelligence Committee has access to our most closely-guarded secrets. And if I am correct that he is a passionate supporter of the Muslim Brotherhood, there is a very real risk that Americans will die as a result,” Cruz warned.”We have American service men and women in harm’s way fighting Muslim Brotherhood terrorists right now. And we also have intelligence covert operatives heroically going undercover trying to anticipate and stop terror attacks before they happen, before they kill Americans. We have every reason to believe that Abdul El-Sayed, if he found out, ‘OK, they’re about to apprehend these terrorists,’ that he would let those terrorists know,” Cruz claimed.HALEY STEVENS’ FIANCE HAMMERS EL-SAYED, SAYS HE’LL VOTE FOR ROGERSThe El-Sayed and Rogers campaigns did not immediately respond to Fox News Digital’s comment requests on Thursday.Speaking to Fox News chief political anchor Bret Baier last week, the Democratic candidate said that he has “never been” and “never will be a member of the Muslim Brotherhood.”MICHIGAN SENATE RIVALS CLASH OVER MUSLIM BROTHERHOOD ALLEGATIONS AS ROGERS DOUBLES DOWN ON EL-SAYED”I am interested in serving the United States. I’m interested in swearing an oath to the Constitution that every senator has swore an oath to,” El-Sayed said.El-Sayed is facing President Donald Trump-backed former Rep. Mike Rogers in the Michigan U.S. Senate contest.EL-SAYED RALLYGOERS URGE ‘MAJOR CHANGE,’ CASH HANDOUTS TO FIGHT COST CRISISCruz made the comments while campaigning for Rogers in the Wolverine State on Wednesday.
Masters winner becomes latest golfer to leave LIV, keeping ‘options open’ for PGA Tour return
LIV Golf is in shambles, and another one has bitten the dust.Sergio Garcia said on social media that he will be playing in the DP World Tour, formerly the European Tour, and is “keeping my options open for a return to the PGA Tour.”The DP World Tour announced earlier this month that it was no longer allowing LIV players to participate in its tournaments.CLICK HERE FOR MORE OUTKICK SPORTS COVERAGE”This tour has been a huge part of my career from the very beginning, and I’m proud to call it home again,” Garcia said in his statement.The 2017 Masters winner also said it is a “goal” to play for Team Europe in the Ryder Cup in Ireland — European golfers must be a member of the DP World Tour in order to be eligible. Thus, with the DP World Tour’s new stipulations, Garcia’s already-slim chances were essentially put to zero.Garcia last played in the Ryder Cup in 2021, several months before jumping to LIV. He has won six times in his 10 appearances.Jon Rahm and Tyrrell Hatton, both Team Europe staples, have already said they are leaving LIV Golf. Louis Oosthuizen is also leaving, and Brooks Koepka and Patrick Reed departed months ago.The PIF halted funding in April to redirect money toward domestic projects and manage financial pressures from the regional war with Iran. Following the decision, PIF governor Yasir Al-Rumayyan resigned from LIV’s board.AUSTIN SMOTHERMAN SETS SIGHTS ON EARNING MASTERS INVITE AFTER PICKING UP BACK-TO-BACK PGA TOUR WINSLIV filed for Chapter 11 bankruptcy in New Jersey last month. Between 2021 and 2026, LIV spent an estimated $5 billion to $8 billion. Bankruptcy filings show the league owes millions of dollars in unpaid compensation to top players, including Rahm, Bryson DeChambeau, Dustin Johnson and Cam Smith.The league’s future depends on a proposed restructuring plan called “LIV 2.0,” but Rahm said the terms of “2.0” are “unacceptable” and he won’t be participating in it. Rahm and Hatton were perhaps the two biggest LIV names to play in DP World Tour events.Under the proposal, London-based private equity firm BC Partners, which has financial ties to player agency GSE Worldwide, would fund a 2027 relaunch. The plan would also give the players majority ownership of the league.LIV has laid off most of its operational staff, left event contractors waiting for payment and faces a lawsuit from the Premier Golf League alleging breach of confidence and conspiracy.Shortly after the PIF pulled its funding, LIV CEO Scott O’Neil said the LIV calendar would not be altered, but that did not occur. The league’s originally-scheduled championship weekend was cancelled, forcing it to be played a week earlier.OutKick’s Alejandro Avila contributed to this report.
WATCH LIVE: President Trump Holds Midterm Rally in Rock Hill, South Carolina – 1 PM ET
President Trump holds a midterm rally in Clemson, South Carolina – October 21, 2026
President Trump is holding another midterm rally in South Carolina this afternoon while stumping for Senator Darline Graham, the sister of late Senator Lindsey Graham, days before the November 3 election.
Trump also spoke in Clemson, South Carolina, last week, where he dropped a hilarious line about Graham’s Democratic opponent.
“Tranny Annie Andrews,” he called her, while railing against her support for transgender surgeries for minors.
Trump Calls South Carolina Democratic Senate Nominee “Tranny Annie Andrews” – Accuses Her of “Child Abuse” and Calls for Her Medical License to Be Revoked (VIDEO)
The President shared a list of his endorsed candidates in the state:
TO THE GREAT PEOPLE OF SOUTH CAROLINA, GET OUT AND VOTE FOR:
– Darline Graham for U.S. Senate
– Alan Wilson for Governor
– Cody Simpson for Agriculture Commissioner
– Jenny Costa Honeycutt for U.S. Congress (SC-01)
– Joe Wilson for U.S. Congress (SC-02)
– Sheri Biggs for U.S. Congress (SC-03)
– William Timmons for U.S. Congress (SC-04)
– Wes Climer for U.S. Congress (SC-05)
– Russell Fry for U.S. Congress (SC-07)
These Great Patriots have my Complete and Total Endorsement — They will never let you down! President DONALD J. TRUMP
swampthevoteusa.com/south-caro
A massive line of supporters had gathered hours early to see President Trump speak.
Via Right Side Broadcasting Network:
The Gateway Pundit is traveling with the President today.
Trump is expected to take the stage at approximately 1 pm ET.
Watch live below:
The post WATCH LIVE: President Trump Holds Midterm Rally in Rock Hill, South Carolina – 1 PM ET appeared first on The Gateway Pundit.
Medicare used AI to pre-approve patient care, and it immediately led to a large drop in medical services
Medicare is testing the use of AI to conduct prior authorizations to target wasteful medical spending
All the reasons Marvell investors are ’freaking out’ as Lumentum deal rumors swirl
Investors are nervous that Marvell would have to pay a big premium — and wait a while for China to approve any deal.
Michael Burry followed Anthropic’s cash and saw familiar names
Most people with an S&P 500 index fund have never put a dollar into Anthropic, yet many own a piece of it anyway. The Vanguard S&P 500 ETF (VOO) holds Amazon.com Inc. (AMZN) and Alphabet Inc. (GOOGL), and both own big stakes in the Claude maker.
That link got louder this week. Anthropic filed its registration statement with the SEC on Monday, Oct. 26, 2026, to list on Nasdaq under the ticker ANT.
Michael Burry, “The Big Short” investor, read the filing and followed the money. His Substack post on Tuesday, Oct. 27, 2026, kept landing on Amazon, Alphabet’s Google, and Microsoft Corp. (MSFT).
Burry argued that this web leaves the system “catastrophically vulnerable” if growth stalls. He tallied about $537 billion in computing and equipment commitments tied to the filing, according to Seeking Alpha.
“There is a lot here but nothing that changes my view,” Burry said.
The dollar figure is striking, but the names explain his worry. Each plays several roles in Anthropic’s business at once.
Also read: Anthropic’s Elvis lawsuit could reach inside Claude itself
The same names show up at every stop
Start with where Anthropic’s money goes. Amazon, Google, and Microsoft supply much of the computing power that trains and runs Claude. Those deals require Anthropic to pay “regardless of usage,” Reuters reported from a draft of the filing.
The list reaches beyond cloud companies. Anthropic expects to pay Elon Musk’s SpaceX (SPCX) about $3.1 billion a month at full capacity, CNBC reported. Bills that size leave little room for a slow quarter.
Now follow it the other way. Amazon and Google are also major Anthropic investors. Amazon even holds convertible notes, a type of loan, and some will convert into Anthropic shares at the listing, according to the S-1.
The same companies help Anthropic sell. About 47% of its 2025 revenue came through Amazon’s and Google’s cloud marketplaces, Reuters reported from a draft filing. The cloud provider keeps a fee on each of those sales.
Anthropic does not hide the tension. Its S-1 warns that these overlapping roles create “complex dynamics that could give rise to conflicts of interest.” It also says some partners build rival models and have not supplied all the computing power it sought.
Amazon’s second-quarter profit included $53.4 billion in non-operating gains, mostly from its Anthropic stake, nearly double its operating income.VCG / Getty Images
The loop already runs through Big Tech profits
This is where Burry’s warning stops being only about Anthropic. Amazon’s second-quarter net income included $53.4 billion in non-operating gains, mostly from its Anthropic investments, according to a press release.
Amazon’s operating income, the profit from its stores, ads, and cloud, was $27.5 billion, as the same release shows. A paper markup outweighed the whole operating business nearly two to one.
Alphabet has felt the same lift. Anthropic stakes were the biggest first-quarter profit driver at both giants, Fortune reported. When they invest more or pledge more cloud capacity, Fortune noted, Anthropic’s valuation tends to climb, and so do their stakes.
That works well while the numbers rise. A stumble at Anthropic, however, would hit their cloud revenue and their investment gains at once.
Growth is what keeps the circle turning
So far, the growth has been real. Anthropic’s second-quarter revenue rose 1,368% from a year earlier, according to the S-1. Compute and infrastructure costs rose 300%, the filing shows, supporting the company’s case that it is getting more efficient.
Then the pace cooled. Anthropic told prospective investors that third-quarter revenue grew about 45% from the second quarter, Reuters reported. Revenue had more than doubled the quarter before.
More Artificial Intelligence:
AI’s biggest business opportunity may not look like AI
AI racks are outgrowing old power: 2 chipmakers have a strategy
BofA splits software into winners and losers as AI agents arrive
Most companies would celebrate that, and Anthropic said it was profitable on an adjusted basis, Bloomberg reported. Its commitments, however, were signed for a steeper curve.
The gap matters because Anthropic typically buys computing capacity 12 to 18 months ahead, according to the S-1, so those costs stay largely fixed. Revenue can slow in any quarter, but the bills arrive on schedule.
Burry is not a neutral reader. Last month, he posted that markets should “tank hard” to keep OpenAI and Anthropic from going public, TechSpot reported. Still, the filing’s own risk section backs his point.
Amazon has felt a paper gain flip before
Amazon shareholders have seen a stake like this reverse. Its holding in Rivian Automotive Inc. (RIVN) produced an $11.8 billion pretax gain in 2021, according to its earnings release.
A year later, Rivian’s sliding shares turned that stake into a $12.7 billion loss, the same release shows. The markdown pushed Amazon to a net loss for 2022.
The lesson is about timing. Rivian traded publicly, so Amazon’s stake reset with its stock price every quarter. The Anthropic stakes mostly reprice when Anthropic raises money, and the listing will change that.
Amazon reports third-quarter results on Thursday, Oct. 29, 2026, its first report since the filing. Next comes the price range in Anthropic’s amended S-1, which will ripple into earnings most index-fund owners already hold.
The biggest players in the AI buildout are increasingly tied together through one another’s stock. Anthropic’s listing is the moment that paper starts trading in public, where it can fall as easily as it rose.
Related: What Jim Cramer is watching as Anthropic heads to Nasdaq
Maker Of Wild Turkey And Grand Marnier Tumbles After North American Sales Go Flat
Maker Of Wild Turkey And Grand Marnier Tumbles After North American Sales Go Flat
Shares of Italian spirits group Campari, maker of Aperol, Wild Turkey, SKYY vodka, and Grand Marnier, plunged the most in European trading since May after an unexpected decline in third-quarter North American sales.”In North America, we are still growing, just to be clear, but the overall growth trajectory for this year is being impacted by the US,” CEO Simon Hunt told analysts on the company’s earnings call.Third-quarter sales rose 3.2% to 777 million euros, exceeding the Bloomberg Consensus estimate of 761.8 million euros. Strength in Europe and developing markets offset weakness elsewhere, allowing Campari to maintain its full-year organic net sales growth forecast of about 3%.Dismal performance in its North American market sent Campari shares spiraling as much as 7.5% in Europe. Organic sales in the region fell 2%, versus expectations of a 2.7% increase, according to Jefferies analysts.Jefferies analyst Edward Mundy said there were “some bright spots,” highlighting the performance of aperitifs and the European business.”However, the group organic print is inline and North America -2.0% misses cons +2.7%,” Mundy wrote in a note to clients earlier.RBC Capital Markets analyst James Edwardes Jones attributed the weakness in North America to the part of the portfolio outside tequila and aperitifs.Barclays analysts noted, “The US is a tale of two portfolios, and the better half is also the more profitable one. The watch points are US softness outside aperitifs and tequila.”UBS analyst Pilar Rocafort wrote, “FY26 guidance was confirmed, although the regional mix has shifted toward stronger Europe and marginally declining North America. The top-line mix could put some pressure on the shares.”Whether gasoline above $4 a gallon is squeezing spending on premium spirits or weaker demand reflects a broader decline in alcohol consumption among younger Americans, Campari faces a challenge shared across the industry: how to reinvigorate its brands in the US.
Tyler Durden
Thu, 10/29/2026 – 12:55
LOL! CNN’s Dana Bash Claims Trump Doesn’t Get Much Pushback, Not as Much as Anyone Else Would (VIDEO)
Screencap of Twitter/X video.
Dana Bash of CNN recently appeared on the Anthony Scaramucci podcast and claimed – with a straight face – that President Trump doesn’t face much pushback, then went on to say he doesn’t face as much as anyone else would.
This is how completely out of touch with reality these people really are.
Does a day even go by when Dana’s own network doesn’t accuse Trump of some insane, imagined, act of wrongdoing? Their entire brand is built on ‘pushing back’ on Trump.
The entire Democrat Party is currently running on ‘pushing back’ on Trump. What is she even talking about?
From Jason Cohen:
CNN’s Dana Bash claims Trump *BARELY* gets “PUSHBACK”
Bash asserted Trump only gets “a little bit” of resistance — and “not as much as any other living human being would.”
Wrong. The reverse is actually true.
Trump gets bombarded with unprecedented “pushback”:
– Assassination attempts
– Constant negative media coverage
– Democrat and Fake News hoaxes
– Impeachments
– Indictments
– Lawfare
– Protests
Just because Trump is the Teflon Don and has mastered The Art of the Comeback doesn’t mean he doesn’t face “pushback.”
Here’s the video:
NEW: CNN’s Dana Bash claims Trump *BARELY* gets “PUSHBACK”
Bash asserted Trump only gets “a little bit” of resistance — and “not as much as any other living human being would.”
Wrong. The reverse is actually true.
Trump gets bombarded with unprecedented “pushback”:
-… pic.twitter.com/xwsaGLxXoS
— Jason Cohen (@JasonJournoDC) October 27, 2026
This is why no one trusts the media anymore.
The fact that Dana Bash can say this and possibly even believes it, shows how out of touch they are with o many average Americans.
Trump supporters have heard nothing but pushback from Dana and her media colleagues for more than a decade now.
The post LOL! CNN’s Dana Bash Claims Trump Doesn’t Get Much Pushback, Not as Much as Anyone Else Would (VIDEO) appeared first on The Gateway Pundit.
Welcome to Cambodia: Cruise ship passengers who booked 4-year trip to avoid Trump now facing new shock
A cruise ship company offered a multi-year trip for people who were upset that President Donald Trump had won a second term and wanted to avoid the U.S. during that time.
They paid tens of thousands, hundreds of thousands of dollars to live on the Villa Vie Odyssey cruise ship for the term.
Now they’re not.
That’s after the cruise ship corporation ran out of money and ordered the passengers, hundreds of them, off the ship to find their own accommodations in Cambodia. And to find their own travel home.
A report at Reuters cited the situation of Paul and Lynn Montoya, from Colorado, who said they sold their house and cars so they could buy a $179,000 cabin on the ship, paying another $6,000 a month in “fees.”
It lasted 17 months until the cruise company ordered them, and 200 others, to take their pets, their personal items, and leave the ship.
Cruise line offers 4-year voyage for those wanting to leave the USA because Trump won https://t.co/MslBj2EQZp
— Not the Bee (@Not_the_Bee) November 12, 2024
A U.S. cruise ship on an around-the-world voyage that touted its cabins as floating homes suspended its three-year voyage in Cambodia due to fuel costs, forcing hundreds of passengers to disembark. https://t.co/zwf99BE8h7 https://t.co/oseNang2or
— CBS Evening News with Tony Dokoupil (@CBSEveningNews) October 28, 2026
Couple who paid $1 MILLION to travel on ‘cruise for life’ say they have no regrets despite being dumped in Cambodia when company ran out of cash https://t.co/QoZem7Inqj
— Daily Mail (@DailyMail) October 28, 2026
Passengers on an “eternal” American cruise unexpectedly disembarked in Cambodia due to fuel costs. Some passengers had sold their homes and all their possessions in order to live permanently at sea. Around 200 passengers found themselves stranded. People were given only a few hours to prepare. The organizers even failed to help them find accommodation in nearby hotels. The cruise began in 2024 and was supposed to last for several years. Fuel costs had risen from $1800 to $6000-8000 (from 145,000 to 484,000-645,000 rubles) per cabin per month. The company itself claims that it is looking for temporary housing options. By the way, this is the same cruise company that, in 2024, offered to spend the duration of Trump’s term in office on a round-the-world cruise. Now, Trump is simply obligated to save this cruise!
— Sprinter Press (@Sprinter_Press) October 29, 2026
Residents of the Villa Vie Odyssey cruise ship were left stranded and at a loss in the Cambodian port city of Sihanoukville after being told to leave the vessel, saying the operator had run out of money to pay for fuel https://t.co/9Ekw1dmlMQ https://t.co/NS18N7Bpzl
— Reuters (@Reuters) October 28, 2026
The report said Paul Montoya confirmed, “We just saw it as a great opportunity to be able to see the world.”
He said, “They’ve run out of money. That’s why they couldn’t buy fuel. They’ve even had difficulties paying the crew on the ship, which even makes it more difficult. So we’re really not expecting any money back.”
The company said it was trying to restructure.
Paul Montoya explained there were signs of trouble: “And then when we got to Cambodia, absolutely no internet. And the food quality began to deteriorate about three months ago, and we knew that the company was running out of money at that time.”
Not the Bee reported, “Rather than keep them apprised of the situation and offer them options, the cruise line gave their passengers only eight hours to get off the ship and find lodging in Cambodia.”
The cruise line blamed Trump.
Its statement said, “Since the (Iran) conflict began in late February, we have taken significant steps to reduce fuel consumption, including slowing the itinerary and spending more time in port. Those measures have not been enough to offset the extraordinary increase in fuel costs, and we have been unable to continue carrying the resulting operating losses.”